Dr Parmar completed his Undergraduate training at the Southampton University Hospitals, followed by Respiratory and General Medicine on the Wessex Specialist Registrar rotation. He completed a PhD in the Department of Medicine at Addenbrookes Hospital and St Catharine’s College Cambridge. Dr Parmar’s thesis examined the impact of changes in conformations of α1-antitrypsin on the biology of neutrophil function in relationship to inflammation in patients with emphysema.
This period of academic training was followed by a year post CCST fellowship, specialist training on the Lung Transplant Program at the University of Toronto.
Clinical lung transplantation, interventional bronchoscopy.
Research Interests
Obliterative bronchiolits.
BM (Soton) 1990
MRCP (Lond) 1993
PhD (Cantab) 2002
FRCP (Lond) 2009
FFICM
ISHLT
BTS
Parmar J S, Taylor I, Roath O S & JL Francis. Whole blood procoagulant activity in cancer patients. Blood Coag and Fibrinolysis. 1990;1 :127-32
Parmar JS & DA Lomas. Alpha-1-antitrypsin deficiency, the serpinopathies and conformation disease. Journal of the Royal College of Physicians. 2000;(34):295-300
Parmar JS, Mahadeva R et al. Polymers of 1-antitrypsin are chemotactic for human neutrophils: a new paradigm for the pathogenesis of emphysema. Am J Respir Cell Mol Biol. 2002;26(6):723-30
Parmar JS, et al. Profound adrenal suppression: Secondary to low dose inhaled fluticasone and Itraconazole in a patient with ABPA and cystic fibrosis. Thorax. 2002;57(8):749-50
Shute J, Parmar JS et al. Urinary GAG’s are elevated in acute severe asthmatics. A role for eosinophil –derived gelatinase B. Int Arch Allergy Immun. 1997;113(1-3):366-9
Fielden J, Parmar JS et al. Mortality and refusal of ICU admission. Lancet. 1997;350(9081):883-884
Renshaw SA, Parmar JS, et al. Acceleration of human neutrophil apoptosis by tumour necrosis factor-related apoptosis –inducing ligand (TRAIL). J Immunology. 2003 Jan 15;170(2):1027-33
D McKeown, Day A, Parmar JS, et al. Hepatocellular carcinoma in a patient with cystic fibrosis related liver disease. J Cyst Fibro. 2004 (3):193-95
Mahadeva R, Atkinson C, Li Z, Stewart S, Janciauskiene S, Kelley DG, Parmar JS, et al. Polymers of Z a1-antitrypsin Co-Localize with Neutrophils in Emphysematous Alveoli and Are Chemotactic in Vivo. Am J Pathol. 2005 Feb;166(2):377-386.
Parmar JS and Nasser. Antibiotics and the Development of allergies in cystic fibrosis. Thorax.2005; 60: 517-520
Church AC, Sivasothy P, Parmar JS, Foweraker J. Mediastinal abscess after lung transplantation secondary to Burkholderia gladioli infection. J Heart Lung Transplant. 2009 May;28(5):511-4.
Parmar JS et al. Invited Commentary: Oro-pharangeal Dysphagia and lung transplantation. Ann Thorac Surg.2010; 90: 1628-1629
Berman M, Goldsmith K, Jenkins D, Sudarshan C, Catarino P, Sukumaran N, Dunning J, Sharples LD, Tsui S, Parmar JS. Comparison of outcomes from smoking and non-smoking donors: thirteen-year experience. Ann Thorac Surg. 2010 Dec;90(6):1786-92.
Banerjee SK, Santhanakrishnan K, Shapiro L, Dunning J, Tsui S, Parmar JS. Successful stenting of anastomotic stenosis of the left pulmonary artery after single lung transplantation. Eur Respir Rev. 2011 Mar 1;20(119):59-62.
Shah PL, Slebos DJ, Cardoso PF, Cetti E, Voelker K, Levine B, Russell ME, Goldin J, Brown M, Cooper JD, Sybrecht GW. Bronchoscopic lung-volume reduction with Exhale airway stents for emphysema (EASE trial): randomised, sham-controlled, multicentre trial. EASE trial study group. Lancet. 2011 Sep 10;378(9795):997-1005.
Banerjee SK, Santhanakrishnan K, Tsui S, Parmar JS.Cavitatory lung disease in thoracic transplant recipients receiving sirolimus. J Heart Lung Transplant. 2012 Mar 5
Mydin M, Calvert P, Jenkins DP, Parmar JS. Percutaneous dilatation of right inferior pulmonary vein stenosis following single-lung transplant. Interactive CardioVascular and Thoracic Surgery 0 (2012) 1–3.
Parmar JS, John Dunning and Stephen Large. Radiological patterns of primary graft dysfunction after lung transplantation. Interact CardioVasc Thorac Surg (2012) 14 (6): 791.
Bonser RS, Taylor R, Collett D, Thomas HL, Dark JH, Neuberger J. Effect of donor smoking on survival after lung transplantation: a cohort study of a prospective registry. Cardiothoracic Advisory Group to NHS Blood and Transplant and the Association of Lung Transplant Physicians (UK). Lancet. 2012 Aug 25;380(9843):747-55.
Contact details:
SwitchBoard: 01223 638000
Secretary
Catherine Gabriolek
Telephone: 01223 639138
Email: catherine.gabriolek@nhs.net